Alzheimer's disease: the amyloid cascade hypothesis

Science. 1992 Apr 10;256(5054):184-5. doi: 10.1126/science.1566067.
No abstract available

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / etiology*
  • Alzheimer Disease / genetics
  • Alzheimer Disease / physiopathology
  • Amyloid / genetics*
  • Amyloid / metabolism
  • Amyloid / physiology
  • Amyloid beta-Protein Precursor / genetics
  • Brain / pathology
  • Brain / physiopathology
  • Cell Death
  • Humans
  • Mutation*
  • Neurofibrillary Tangles / physiology

Substances

  • Amyloid
  • Amyloid beta-Protein Precursor