Antibacterial and antifungal activity of pinosylvin, a constituent of pine

S K Lee; H J Lee; H Y Min; E J Park; K M Lee; Y H Ahn; Y J Cho; J H Pyee

doi:10.1016/j.fitote.2004.12.004

Antibacterial and antifungal activity of pinosylvin, a constituent of pine

Fitoterapia. 2005 Mar;76(2):258-60. doi: 10.1016/j.fitote.2004.12.004.

Authors

S K Lee¹, H J Lee, H Y Min, E J Park, K M Lee, Y H Ahn, Y J Cho, J H Pyee

Affiliation

¹ College of Pharmacy, Ewha Womans University, Seoul 120-750, South Korea. sklee@ewha.ac.kr

PMID: 15752644
DOI: 10.1016/j.fitote.2004.12.004

Abstract

The antibacterial and antifungal activities of pinosylvin (3,5-dihydroxy-trans-stilbene), a constituent of pine, were studied and compared with those of resveratrol (3,5,4'-trihydroxy-trans-stilbene). Pinosylvin exhibited more potent growth inhibitory activity against Candida albicans and Saccharomyces cerevisiae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / pharmacology*
Anti-Bacterial Agents / therapeutic use
Antifungal Agents / administration & dosage
Antifungal Agents / pharmacology*
Antifungal Agents / therapeutic use
Candida albicans / drug effects
Escherichia coli / drug effects
Humans
Microbial Sensitivity Tests
Phytotherapy*
Pinus*
Plant Leaves
Plant Oils / administration & dosage
Plant Oils / pharmacology
Plant Oils / therapeutic use
Saccharomyces / drug effects
Staphylococcus aureus / drug effects
Stilbenes / administration & dosage
Stilbenes / pharmacology*
Stilbenes / therapeutic use

Substances

Anti-Bacterial Agents
Antifungal Agents
Plant Oils
Stilbenes
pinosylvin