Pharmacologic agents associated with QT interval prolongation

J Fam Pract. 2005 Jun:Suppl:S8-S14.

Abstract

Diverse classes of medications are associated with QT interval prolongation and expose patients to the risk of potentially fatal ventricular arrhythmias. Clinicians can minimize adverse events by avoiding prescription of multiple medications associated with QT interval prolongation in high-risk patients.

Publication types

  • Review

MeSH terms

  • Anti-Arrhythmia Agents / adverse effects*
  • Anti-Bacterial Agents / adverse effects*
  • Antidepressive Agents, Tricyclic / adverse effects*
  • Antipsychotic Agents / adverse effects*
  • Death, Sudden, Cardiac / etiology
  • Fluoroquinolones / adverse effects
  • Heart Rate / drug effects
  • Humans
  • Long QT Syndrome / chemically induced*
  • Long QT Syndrome / complications
  • Long QT Syndrome / diagnosis
  • Macrolides / adverse effects
  • Risk Factors
  • Torsades de Pointes / chemically induced
  • Torsades de Pointes / diagnosis

Substances

  • Anti-Arrhythmia Agents
  • Anti-Bacterial Agents
  • Antidepressive Agents, Tricyclic
  • Antipsychotic Agents
  • Fluoroquinolones
  • Macrolides