[Effect of phenibut on the behavior of experimental animals under conditions of voluntary chronic alcoholism]

Eksp Klin Farmakol. 2005 May-Jun;68(3):42-5.
[Article in Russian]

Abstract

The effect of phenibut on the locomotor and orientation-research activity, as well as on the alcohol and food motivation, was studied on experimental animals under conditions of voluntary chronic alcoholism. Phenibut decreased the manifestations of alcohol-induced behavioral disorders and reduced alcohol motivation.

MeSH terms

  • Alcohol Drinking / physiopathology*
  • Alcoholism / physiopathology*
  • Animals
  • Behavior, Animal / drug effects
  • GABA Agonists / pharmacology*
  • Male
  • Motor Activity / drug effects*
  • Orientation / drug effects*
  • Rats
  • gamma-Aminobutyric Acid / analogs & derivatives*
  • gamma-Aminobutyric Acid / pharmacology

Substances

  • GABA Agonists
  • gamma-Aminobutyric Acid
  • 4-amino-3-phenylbutyric acid