The evolution of late life

Ageing Res Rev. 2006 Feb;5(1):14-32. doi: 10.1016/j.arr.2005.06.003. Epub 2005 Aug 8.

Abstract

Late life is a distinct phase of life characterized by a cessation in the deterioration of survivorship and fecundity characteristic of normal aging. Several theories have been proposed to explain non-aging at late ages, specifically with regards to late-life mortality-rate plateaus. All such theories must be compatible with formal evolutionary theory and experimental findings. Here, we develop a critique of theories of late life based on evolutionary biology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Age Factors
  • Aging / genetics
  • Aging / physiology
  • Biological Evolution*
  • Fertility / genetics
  • Genetic Variation
  • Genetics, Population
  • Humans
  • Longevity / genetics*
  • Longevity / physiology
  • Mortality
  • Selection, Genetic