The application of phenylmethanethiol and benzenethiol derivatives as odorless organosulfur reagents in the synthesis of thiosugars and thioglycosides

Jun-ya Hasegawa; Masahiro Hamada; Tetsuo Miyamoto; Kiyoharu Nishide; Tetsuya Kajimoto; Jun-ichi Uenishi; Manabu Node

doi:10.1016/j.carres.2005.07.011

The application of phenylmethanethiol and benzenethiol derivatives as odorless organosulfur reagents in the synthesis of thiosugars and thioglycosides

Carbohydr Res. 2005 Oct 31;340(15):2360-8. doi: 10.1016/j.carres.2005.07.011.

Authors

Jun-ya Hasegawa¹, Masahiro Hamada, Tetsuo Miyamoto, Kiyoharu Nishide, Tetsuya Kajimoto, Jun-ichi Uenishi, Manabu Node

Affiliation

¹ Department of Pharmaceutical Manufacturing Chemistry, 21st Century COE program, Kyoto Pharmaceutical University, Misasagi, Kyoto 607-8414, Japan.

PMID: 16143318
DOI: 10.1016/j.carres.2005.07.011

Abstract

p-octyloxyphenylmethanethiol and p-dodecylbenzenethiol were prepared as new odorless organosulfur reagents. Thiosugars and thioglycosides were synthesized using these reagents without encountering any malodorous procedures.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Indicators and Reagents
Odorants
Pentoses / chemical synthesis*
Sulfhydryl Compounds / chemistry*
Sulfur Compounds / chemical synthesis*
Thioglycosides / chemical synthesis*

Substances

4-dodecylbenzenethiol
4-octyloxyphenylmethanethiol
Indicators and Reagents
Pentoses
Sulfhydryl Compounds
Sulfur Compounds
Thioglycosides