Clinical observation on effect of triptolide tablet in treating patients with psoriasis vulgaris

Chin J Integr Med. 2005 Jun;11(2):147-8. doi: 10.1007/BF02836473.

Abstract

Objective: To investigate the effects of triptolide tablet in the treatment of patients with psoriasis vulgaris.

Methods: By an open clinical study of 103 patients with psoriasis vulgaris. Psoriasis area severity index (PASI) was measured and recorded before and after treatment for efficacy evaluation.

Results: Of the 103 patients, markedly effective was got in 41 (39.7%), improved in 37 (35.8%) and ineffective in 25 (24.5%), the total effective rate being 75.7%, and the adverse reaction was shown only in few patients with decreased WBC during the treatment period.

Conclusion: Triptolide tablet is effective for the treatment of psoriasis vulgaris during the one-year follow-up.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Diterpenes / administration & dosage*
  • Diterpenes / adverse effects
  • Epoxy Compounds
  • Female
  • Follow-Up Studies
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Immunosuppressive Agents / adverse effects
  • Male
  • Middle Aged
  • Phenanthrenes / administration & dosage*
  • Phenanthrenes / adverse effects
  • Psoriasis / drug therapy*
  • Tablets
  • Treatment Outcome

Substances

  • Diterpenes
  • Epoxy Compounds
  • Immunosuppressive Agents
  • Phenanthrenes
  • Tablets
  • triptolide