Blood-brain barrier permeability in "healthy" infected and stressed neonates

D Anagnostakis; J Messaritakis; D Damianos; H Mandyla

doi:10.1016/s0022-3476(05)81207-7

Blood-brain barrier permeability in "healthy" infected and stressed neonates

J Pediatr. 1992 Aug;121(2):291-4. doi: 10.1016/s0022-3476(05)81207-7.

Authors

D Anagnostakis¹, J Messaritakis, D Damianos, H Mandyla

Affiliation

¹ First Department of Pediatrics, Athens University, Greece.

PMID: 1640301
DOI: 10.1016/s0022-3476(05)81207-7

Abstract

The assessment of the blood-brain barrier permeability (BBBP) showed that BBBP values were higher in stressed neonates and those with bacterial meningitis than in "healthy" infants or neonates with aseptic meningitis. The BBBP determination may be helpful in differentiating bacterial from aseptic meningitis; the high BBBP should be considered in the management of stressed neonates.

MeSH terms

Asphyxia Neonatorum / physiopathology
Blood-Brain Barrier / physiology*
Diagnosis, Differential
Heart Defects, Congenital / physiopathology
Humans
Infant, Newborn / physiology*
Meningitis, Aseptic / diagnosis
Meningitis, Aseptic / physiopathology*
Meningitis, Bacterial / diagnosis
Meningitis, Bacterial / physiopathology*
Permeability
Stress, Physiological / physiopathology*