Zinc: the new antidepressant?

Nutr Rev. 2006 Jan;64(1):39-42. doi: 10.1111/j.1753-4887.2006.tb00171.x.

Abstract

Low serum zinc levels have been linked to major depression. Furthermore, zinc treatment has been shown to have an antidepressant effect. With the hope of understanding the role of zinc in mood disorders, recent work has begun to explore possible mechanisms of zinc action on serotonin uptake in the brain.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / therapeutic use*
  • Brain / metabolism
  • Depression / drug therapy*
  • Depression / etiology
  • Depression / metabolism
  • Humans
  • Serotonin / metabolism*
  • Trace Elements / blood
  • Trace Elements / deficiency*
  • Trace Elements / therapeutic use
  • Zinc / blood
  • Zinc / deficiency*
  • Zinc / therapeutic use

Substances

  • Antidepressive Agents
  • Trace Elements
  • Serotonin
  • Zinc