Sequence of a rotavirus gene 4 associated with unique biologic properties

Abstract

The genome segment 4 of the simian rotavirus variant SA 11-4F was sequenced. This gene is of probable bovine origin, and it contains a few amino acid differences when compared with other SA 11 variants (4 fm and fem) that were isolated independently and that have fast migration patterns of their gene 4 segments. Hypotheses for the role of sequence changes are made relative to the unique properties of the SA 11-4F variant.