Nonprotein amino acids from spark discharges and their comparison with the murchison meteorite amino acids

Y Wolman; W J Haverland; S L Miller

doi:10.1073/pnas.69.4.809

Nonprotein amino acids from spark discharges and their comparison with the murchison meteorite amino acids

Proc Natl Acad Sci U S A. 1972 Apr;69(4):809-11. doi: 10.1073/pnas.69.4.809.

Authors

Y Wolman¹, W J Haverland, S L Miller

Affiliation

¹ Department of Chemistry, University of California, San Diego, La Jolla, Calif. 92037.

Abstract

All the nonprotein amino acids found in the Murchison meteorite are products of the action of electric discharge on a mixture of methane, nitrogen, and water with traces of ammonia. These amino acids include alpha-amino-n-butyric acid, alpha-aminoisobutyric acid, norvaline, isovaline, pipecolic acid, beta-alanine, beta-amino-n-butyric acid, beta-aminoisobutyric acid, gamma-aminobutyric acid, sarcosine, N-ethylglycine, and N-methylalanine. In addition, norleucine, alloisoleucine, N-propylglycine, N-isopropylglycine, N-methyl-beta-alanine, N-ethyl-beta-alanine alpha,beta-diaminopropionic acid, isoserine, alpha,gamma-diaminobutyric acid, and alpha-hydroxy-gamma-aminobutyric acid are produced by the electric discharge, but have not been found in the meteorite.