Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms

Chem Rev. 2006 Aug;106(8):3468-96. doi: 10.1021/cr0503097.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis*
  • Anti-Bacterial Agents / chemistry
  • Catalysis
  • Models, Molecular
  • Peptide Synthases / chemistry*
  • Polyketide Synthases / chemistry*
  • Protein Conformation

Substances

  • Anti-Bacterial Agents
  • Polyketide Synthases
  • Peptide Synthases
  • non-ribosomal peptide synthase