[Psychopharmacological treatment of behavioral and psychological symptoms in dementia]

Ugeskr Laeger. 2006 Oct 2;168(40):3429-32.
[Article in Danish]

Abstract

Behavioural and psychological symptoms of dementia (BPSD) are common and can dominate disease presentation. Antidepressions are commonly prescribed for depressive symptoms, but the evidence to support this practice is weak. The atypical antipsychotics risperidone and olanzepine have significant efficacy for the treatment of aggression and risperidone is also efficacious in the treatment of psychosis, but both with substantially increased risk of stroke. There are no newer studies of benzodiazepines in the treatment of anxiety and in old studies the efficacy are doubtful.

Publication types

  • Review

MeSH terms

  • Anti-Anxiety Agents / adverse effects
  • Anti-Anxiety Agents / therapeutic use
  • Anticonvulsants / adverse effects
  • Anticonvulsants / therapeutic use
  • Antidepressive Agents / adverse effects
  • Antidepressive Agents / therapeutic use*
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Benzodiazepines / adverse effects
  • Benzodiazepines / therapeutic use
  • Dementia / complications
  • Dementia / drug therapy*
  • Dementia / psychology
  • Humans
  • Mental Disorders / complications
  • Mental Disorders / drug therapy*
  • Olanzapine
  • Risperidone / adverse effects
  • Risperidone / therapeutic use
  • Selective Serotonin Reuptake Inhibitors / adverse effects
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Treatment Outcome

Substances

  • Anti-Anxiety Agents
  • Anticonvulsants
  • Antidepressive Agents
  • Antipsychotic Agents
  • Serotonin Uptake Inhibitors
  • Benzodiazepines
  • Risperidone
  • Olanzapine