Stereochemical reassignment of Mehta and Kundu's spiculoic acid a analogue

Org Lett. 2006 Nov 23;8(24):5537-40. doi: 10.1021/ol062361a.

Abstract

A close examination of Mehta and Kundu's synthesis of an analogue of spiculoic acid A revealed discrepancies between their proposed structure and corresponding data. A revised structure is proposed for Mehta and Kundu's analogue after a careful analysis of their key synthetic transformations and published data. [reaction: see text].

MeSH terms

  • Animals
  • Carboxylic Acids / chemistry*
  • Indans / chemistry*
  • Indicators and Reagents
  • Molecular Conformation
  • Plakortis / chemistry
  • Stereoisomerism

Substances

  • Carboxylic Acids
  • Indans
  • Indicators and Reagents
  • spiculoic acid A