Copper deficiency myeloneuropathy resembling B12 deficiency: partial resolution of MR imaging findings with copper supplementation

B P Goodman; B W Chong; A C Patel; G P Fletcher; B E Smith

Copper deficiency myeloneuropathy resembling B12 deficiency: partial resolution of MR imaging findings with copper supplementation

AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2112-4.

Authors

B P Goodman¹, B W Chong, A C Patel, G P Fletcher, B E Smith

Affiliation

¹ Department of Neurology, Mayo Clinic Scottsdale, Scottsdale, AZ 85259, USA. goodman.brent@mayo.edu

PMID: 17110677
PMCID: PMC7977229

Abstract

Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B(12) deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B(12) deficiency, which partially reversed following copper supplementation. This is, to our knowledge, the first described case of radiographic improvement with copper supplementation.

Publication types

Case Reports

MeSH terms

Copper / deficiency*
Copper / therapeutic use
Diagnosis, Differential
Female
Humans
Magnetic Resonance Imaging*
Middle Aged
Spinal Cord Diseases / diagnosis*
Spinal Cord Diseases / drug therapy
Vitamin B 12 Deficiency / diagnosis*

Substances

Copper