The effect of beta-glucan on the glycemic and insulin index

Eur J Clin Nutr. 2007 Jun;61(6):779-85. doi: 10.1038/sj.ejcn.1602561. Epub 2006 Dec 6.

Abstract

Objective: To determine the effects of oat products with increasing beta-glucan content on the glycemic (GI) and insulin indexes (II) of oat products, and to establish the effect of physical properties of beta-glucan on these physiological responses.

Design: Test group (n=10) randomly attended to three glucose tolerance tests and glycemic response tests for four oat bran products.

Settings: Functional Foods Forum and the Department of Food Chemistry, University of Turku, and the Department of Food Technology, University of Helsinki.

Subjects: One male and nine female volunteers were recruited from university students and staff, and all completed the study.

Interventions: GI and II of different products were calculated for each subject using the average of parallel glucose tolerance tests and the subsequent glycemic/insulinemic responses for each product. Average indexes for products were calculated according to the individual data.

Results: The glycemic responses to oat products with increasing amounts of beta-glucan had lower peak values than the reference glucose load. The amount of extractable beta-glucan had a high correlation between the glycemic and insulinemic response.

Conclusion: In addition to the total amount of beta-glucan in oat products, the amount of extractable beta-glucan in oat products explains the magnitude of the decrease in glycemic responses to carbohydrate products.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Area Under Curve
  • Avena / chemistry*
  • Blood Glucose / metabolism*
  • Cross-Over Studies
  • Digestion / drug effects
  • Dose-Response Relationship, Drug
  • Female
  • Glucose Tolerance Test
  • Glycemic Index / drug effects*
  • Humans
  • Insulin / blood*
  • Intestinal Absorption / drug effects
  • Male
  • beta-Glucans / pharmacokinetics*

Substances

  • Blood Glucose
  • Insulin
  • beta-Glucans