DNA repair and survival in lung cancer--the two faces of Janus

N Engl J Med. 2007 Feb 22;356(8):771-3. doi: 10.1056/NEJMp068308.
No abstract available

Publication types

  • Comment

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Non-Small-Cell Lung / drug therapy
  • Carcinoma, Non-Small-Cell Lung / genetics*
  • DNA Repair*
  • DNA, Neoplasm
  • DNA-Binding Proteins / genetics
  • DNA-Binding Proteins / metabolism*
  • Endonucleases / genetics
  • Endonucleases / metabolism*
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / genetics*
  • Platinum Compounds / administration & dosage
  • Platinum Compounds / adverse effects
  • Prognosis
  • Ribonucleoside Diphosphate Reductase
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism*

Substances

  • DNA, Neoplasm
  • DNA-Binding Proteins
  • Platinum Compounds
  • Tumor Suppressor Proteins
  • RRM1 protein, human
  • Ribonucleoside Diphosphate Reductase
  • ERCC1 protein, human
  • Endonucleases