Abstract
A carbapenem-resistant isolate of Escherichia coli was identified that possessed a 23-kb plasmid encoding Klebsiella pneumoniae carbapenemase type 2 (KPC-2). A subsequent surveillance study involving hospitals in Brooklyn, New York, revealed that, among 1417 E. coli isolates, 7 isolates (from 3 hospitals) possessed bla(KPC-2). E. coli possessing KPC-2 is emerging in our region, and improved methods for detection are urgently needed.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use*
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Bacterial Proteins / metabolism*
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Carbapenems / pharmacology
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Cross Infection / epidemiology
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Cross Infection / microbiology
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Disease Outbreaks*
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Drug Resistance, Bacterial
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Escherichia coli / classification
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Escherichia coli / enzymology*
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Escherichia coli Infections / diagnosis
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Escherichia coli Infections / epidemiology*
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Humans
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Incidence
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Male
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Microbial Sensitivity Tests
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New York City / epidemiology
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Polymerase Chain Reaction
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Population Surveillance
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beta-Lactamases / metabolism*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Carbapenems
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beta-lactamase KPC-2
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beta-Lactamases
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carbapenemase