Ubiquitin-proteasome: pallbearer carries the deceased to the grave

Immunity. 2007 Oct;27(4):541-4. doi: 10.1016/j.immuni.2007.10.003.

Abstract

Phagocytosis is a complex process that involves multiple cellular functions. In this issue of Immunity, Silva et al. (2007) report that a protein ubiquitylation complex and the proteasome are required for the clearance of apoptotic cells in Drosophila.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Apoptosis / physiology*
  • Macrophages / immunology
  • Macrophages / metabolism
  • Models, Immunological*
  • Phagocytosis / physiology*
  • Proteasome Endopeptidase Complex / metabolism*
  • Ubiquitin / metabolism*

Substances

  • Ubiquitin
  • Proteasome Endopeptidase Complex