Pharmacotherapy for insomnia

Clin Geriatr Med. 2008 Feb;24(1):93-105, vii. doi: 10.1016/j.cger.2007.08.009.

Abstract

Hypnotics are commonly use in the treatment of insomnia, and hypnotic use among older adults is more prevalent than with younger adults. Unfortunately, the use of hypnotics is not well studied in the ever-growing geriatric population and the magnitude of the medication benefit is usually not impressive. Insomnia in older adults is usually treated with benzodiazepines, nonbenzodiazepines, and other agents, such as trazodone, valerian, and melatonin. Using appropriately selected agents and therapy initiated with a low dose and careful monitoring of the patient could minimize common unwanted side effects.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / therapeutic use
  • Azabicyclo Compounds / therapeutic use
  • Central Nervous System Depressants / therapeutic use
  • Eszopiclone
  • GABA Agonists / therapeutic use
  • GABA-A Receptor Antagonists*
  • Humans
  • Indenes / therapeutic use
  • Melatonin / therapeutic use
  • Phytotherapy
  • Piperazines / therapeutic use
  • Pyridines / therapeutic use
  • Sleep Initiation and Maintenance Disorders / drug therapy*
  • Valerian
  • Zolpidem

Substances

  • Antidepressive Agents
  • Azabicyclo Compounds
  • Central Nervous System Depressants
  • GABA Agonists
  • GABA-A Receptor Antagonists
  • Indenes
  • Piperazines
  • Pyridines
  • Zolpidem
  • ramelteon
  • Melatonin
  • Eszopiclone