Adamantane-resistant influenza infection during the 2004-05 season

Emerg Infect Dis. 2008 Jan;14(1):173-6. doi: 10.3201/eid1401.070460.

Abstract

Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. We identified adamantane resistance in 47% of 152 influenza A virus (H3N2) isolates collected during 2005. Resistant and susceptible viruses caused similar symptoms and illness duration. The prevalence of resistance was highest in children.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adamantane / therapeutic use*
  • Adolescent
  • Adult
  • Aged
  • Antiviral Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Disease Outbreaks*
  • Drug Resistance, Viral / genetics*
  • Female
  • Humans
  • Infant
  • Influenza A Virus, H3N2 Subtype* / drug effects
  • Influenza A Virus, H3N2 Subtype* / genetics
  • Influenza A Virus, H3N2 Subtype* / isolation & purification
  • Influenza B virus / drug effects
  • Influenza, Human / drug therapy*
  • Influenza, Human / epidemiology
  • Influenza, Human / genetics
  • Male
  • Middle Aged
  • Wisconsin / epidemiology

Substances

  • Antiviral Agents
  • Adamantane