Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community

J Neuropsychiatry Clin Neurosci. 2008 Winter;20(1):101-5. doi: 10.1176/jnp.2008.20.1.101.

Abstract

The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds ratio for diagnosis of major depressive disorder (4.7, 95% confidence interval [1.6, 14.5]) and panic disorder (12.9 [3.6, 46.0]) and comorbidity of major depressive disorder and panic disorder (9.7 [1.4, 69.0]) in the past 12 months suggested a strong association between restless legs syndrome and major depressive disorder and/or panic disorder.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Comorbidity
  • Cross-Sectional Studies
  • Depressive Disorder, Major / epidemiology*
  • Diagnostic and Statistical Manual of Mental Disorders*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Panic Disorder / epidemiology*
  • Residence Characteristics*
  • Restless Legs Syndrome / epidemiology*
  • Surveys and Questionnaires