The Foodborne Diseases Active Surveillance Network (FoodNet) of CDC's Emerging Infections Program collects data from 10 U.S. states regarding diseases caused by pathogens commonly transmitted through food. FoodNet quantifies and monitors the incidence of these infections by conducting active, population-based surveillance for laboratory-confirmed infections. This report describes preliminary surveillance data for 2007 and compares them with data for previous years. In 2007, the estimated incidence of infections caused by Campylobacter, Listeria, Shiga toxin-producing Escherichia coli O157 (STEC O157), Salmonella, Shigella, Vibrio, and Yersinia did not change significantly, and Cryptosporidium infections increased compared with 2004-2006. Progress toward the targets for Healthy People 2010 national health objectives and targets regarding the incidence of foodborne infections occurred before 2004; however, none of the targets were reached in 2007. Salmonella incidence was the furthest from its national health target, suggesting that reaching this target will require new approaches.