Abstract
The survival ofTrypanosoma brucei relies on the sucessive expression of a single surface protein gene from a family of around 1,000 genes. This switching appears to be partly dictated by epigenetic changes in chromatin.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Antigenic Variation / genetics*
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Antigenic Variation / immunology*
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Models, Biological
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Protozoan Proteins / genetics
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Protozoan Proteins / immunology
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Trypanosoma brucei brucei / genetics*
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Trypanosoma brucei brucei / immunology*
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Variant Surface Glycoproteins, Trypanosoma / genetics
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Variant Surface Glycoproteins, Trypanosoma / immunology
Substances
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Protozoan Proteins
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Variant Surface Glycoproteins, Trypanosoma