Abstract
A seven-year-old, 31 kg male neutered Labrador was investigated for signs of feminisation syndrome and prostatic disease four years after castration and removal of a testicular sertoli cell tumour (SCT). Investigations revealed an elevated serum oestradiol-17beta concentration, a pulmonary mass containing fluid high in oestradiol-17beta and cystic changes in the prostate gland. The pulmonary mass was surgically excised and histologically confirmed to be a SCT metastasis. To the authors' knowledge, this is the first reported case of a proven functional extranodal SCT metastasis and the first to be diagnosed by oestradiol-17beta measurement of intralesional fluid.
MeSH terms
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Animals
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Cryptorchidism / veterinary
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Cysts / pathology
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Cysts / veterinary
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Dog Diseases / diagnosis*
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Dog Diseases / pathology
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Dog Diseases / therapy
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Dogs
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Estradiol / analysis*
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Feminization / etiology
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Feminization / veterinary
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Lung Neoplasms / secondary
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Lung Neoplasms / surgery
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Lung Neoplasms / veterinary*
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Male
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Prostate / diagnostic imaging
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Radioimmunoassay / veterinary
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Sertoli Cell Tumor / complications
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Sertoli Cell Tumor / diagnosis
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Sertoli Cell Tumor / secondary
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Sertoli Cell Tumor / veterinary*
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Testicular Neoplasms / complications
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Testicular Neoplasms / diagnosis
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Testicular Neoplasms / pathology
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Testicular Neoplasms / veterinary*
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Treatment Outcome
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Ultrasonography