Results of treatment of 60 patients with festering wounds were comparatively studeid. According to the mode of local treatment the patients were divided into 2 groups: wound irrigation with ozone was carried out in the first group; in the second group local ozone therapy was carried out in combination with low-frequency magnetic fields--ozonomagnetophoresis. Bactericidal effect and antibiotic susceptibility of microflora is more marked using ozonomagnetophoresis. Tendency to purulo-necrotic tissue rejection from wound surface, regress of inflammation exudative stage with natural forming of granulation tissue in relatively short terms, its accelerated maturing and reparation are histologicaly marked.