Mechanism of androgen receptor action

Jin Li; Farook Al-Azzawi

doi:10.1016/j.maturitas.2009.03.008

Mechanism of androgen receptor action

Maturitas. 2009 Jun 20;63(2):142-8. doi: 10.1016/j.maturitas.2009.03.008. Epub 2009 Apr 15.

Authors

Jin Li¹, Farook Al-Azzawi

Affiliation

¹ Gynaecology Research Unit, University Hospitals of Leicester, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom.

PMID: 19372015
DOI: 10.1016/j.maturitas.2009.03.008

Abstract

Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators. We also explore several clinically relevant aspects of the molecular biology of the androgen receptor and its co-regulators.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Androgens / chemistry
Androgens / genetics
Androgens / metabolism*
Bone and Bones / metabolism
Brain / metabolism
Cardiovascular Diseases / metabolism
Female
Humans
Male
Molecular Structure
Muscle, Skeletal / metabolism
Prostatic Neoplasms / metabolism
Receptors, Androgen / chemistry
Receptors, Androgen / genetics
Receptors, Androgen / metabolism*
Signal Transduction / physiology

Substances

Androgens
Receptors, Androgen