DNA topoisomerase I inhibitors: chemistry, biology, and interfacial inhibition

Chem Rev. 2009 Jul;109(7):2894-902. doi: 10.1021/cr900097c.
No abstract available

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Camptothecin / chemistry
  • Camptothecin / pharmacology
  • DNA Damage
  • DNA Repair
  • DNA Topoisomerases, Type I / chemistry
  • DNA Topoisomerases, Type I / metabolism
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Neoplasms / enzymology
  • Topoisomerase I Inhibitors*

Substances

  • Enzyme Inhibitors
  • Topoisomerase I Inhibitors
  • DNA Topoisomerases, Type I
  • Camptothecin