[An experimental study of the spectrum of individual psychotropic activity of clozapine (Leponex)]

Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(11):1710-7.
[Article in Russian]

Abstract

An experimental analysis of the psychotropic activity of Leponex (in a chronic experiment on II cats) in conditions of a group interaction depicted that the preparation processes a definite tranquillizing and antipsychotic effect. In conditions of zoosocial interactions this drug promotes disappearance of neurotic reactions and a resocialization of animals in the zoosocial ierarchy. In tranquillizing doses the preparation has an antihypertensive effect and prevents the development of a long-term tonic hypertension due to emotional stress.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antipsychotic Agents
  • Cats
  • Clozapine / therapeutic use*
  • Diazepam / therapeutic use
  • Dibenzazepines / therapeutic use*
  • Disease Models, Animal
  • Haloperidol / therapeutic use
  • Humans
  • Mental Disorders / drug therapy*
  • Neurotic Disorders / drug therapy
  • Psychotic Disorders / drug therapy
  • Social Behavior
  • Tranquilizing Agents

Substances

  • Antipsychotic Agents
  • Dibenzazepines
  • Tranquilizing Agents
  • Clozapine
  • Haloperidol
  • Diazepam