Epidemiology of antimicrobial resistance among gram-negative organisms recovered from patients in a multistate network of long-term care facilities

Infect Control Hosp Epidemiol. 2009 Aug;30(8):790-3. doi: 10.1086/599070.

Abstract

We identified 1,805 gram-negative organisms in cultures of urine samples obtained over a 10-month period from residents of 63 long-term care facilities. The prevalence of fluoroquinolone resistance in Escherichia coli was 51% (446 of 874 isolates), whereas the prevalences of ceftazidime and imipenem resistance in Klebsiella species were 26% and 6% (84 and 19 of 323 isolates), respectively. The prevalence of resistance varied significantly by facility type, size, and geographic location.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Ceftazidime / therapeutic use
  • Colony Count, Microbial
  • Cross Infection / drug therapy
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Cross Infection / urine
  • Cross-Sectional Studies
  • Delaware / epidemiology
  • Drug Resistance, Bacterial*
  • Escherichia coli / drug effects
  • Escherichia coli / isolation & purification
  • Fluoroquinolones / therapeutic use
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / epidemiology*
  • Gram-Negative Bacterial Infections / microbiology
  • Gram-Negative Bacterial Infections / urine
  • Humans
  • Imipenem / therapeutic use
  • Klebsiella / drug effects
  • Klebsiella / isolation & purification
  • Long-Term Care / statistics & numerical data
  • Microbial Sensitivity Tests
  • New Jersey / epidemiology
  • Pennsylvania / epidemiology
  • Prevalence
  • Proteus mirabilis / drug effects
  • Proteus mirabilis / isolation & purification
  • Skilled Nursing Facilities / statistics & numerical data*

Substances

  • Anti-Bacterial Agents
  • Fluoroquinolones
  • Imipenem
  • Ceftazidime