Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene

Acta Neuropathol. 2009 Nov;118(5):719-20. doi: 10.1007/s00401-009-0593-1. Epub 2009 Oct 21.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Brain / metabolism*
  • Brain / pathology
  • Chromosomes, Human, Pair 3*
  • Endosomal Sorting Complexes Required for Transport / genetics*
  • Female
  • Frontotemporal Dementia / genetics*
  • Frontotemporal Dementia / pathology
  • Humans
  • Inclusion Bodies / metabolism
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Nerve Tissue Proteins / genetics*
  • Pedigree
  • Postmortem Changes
  • RNA-Binding Protein FUS / metabolism
  • Ubiquitin / metabolism

Substances

  • CHMP2B protein, human
  • Endosomal Sorting Complexes Required for Transport
  • Nerve Tissue Proteins
  • RNA-Binding Protein FUS
  • Ubiquitin