MouseIndelDB: a database integrating genomic indel polymorphisms that distinguish mouse strains

Nucleic Acids Res. 2010 Jan;38(Database issue):D600-6. doi: 10.1093/nar/gkp1046. Epub 2009 Nov 20.

Abstract

MouseIndelDB is an integrated database resource containing thousands of previously unreported mouse genomic indel (insertion and deletion) polymorphisms ranging from approximately 100 nt to 10 Kb in size. The database currently includes polymorphisms identified from our alignment of 26 million whole-genome shotgun sequence traces from four laboratory mouse strains mapped against the reference C57BL/6J genome using GMAP. They can be queried on a local level by chromosomal coordinates, nearby gene names or other genomic feature identifiers, or in bulk format using categories including mouse strain(s), class of polymorphism(s) and chromosome number. The results of such queries are presented either as a custom track on the UCSC mouse genome browser or in tabular format. We anticipate that the MouseIndelDB database will be widely useful for research in mammalian genetics, genomics, and evolutionary biology. Access to the MouseIndelDB database is freely available at: http://variation.osu.edu/.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Computational Biology / methods*
  • Computational Biology / trends
  • Databases, Genetic*
  • Databases, Nucleic Acid*
  • Databases, Protein
  • Genome
  • Information Storage and Retrieval / methods
  • Internet
  • Mice
  • Mice, Inbred C57BL
  • Models, Genetic
  • Polymorphism, Genetic*
  • Software
  • Species Specificity
  • User-Computer Interface