N-acetylcysteine, reactive oxygen species and beyond

Cancer Biol Ther. 2010 Jan;9(2):109-10. doi: 10.4161/cbt.9.2.10583. Epub 2010 Jan 10.
No abstract available

Publication types

  • Comment
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acetylcysteine / pharmacology*
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Apoptosis / genetics
  • CASP8 and FADD-Like Apoptosis Regulating Protein / biosynthesis
  • CASP8 and FADD-Like Apoptosis Regulating Protein / genetics
  • Cell Line, Tumor / drug effects
  • Cell Line, Tumor / metabolism
  • Down-Regulation
  • Gene Expression Regulation, Leukemic / drug effects
  • Glutathione / metabolism
  • Glycyrrhetinic Acid / analogs & derivatives
  • Glycyrrhetinic Acid / pharmacology
  • Humans
  • Leukemia, Myeloid, Acute / pathology*
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Neoplasm Proteins / biosynthesis*
  • Neoplasm Proteins / genetics
  • Oxidation-Reduction
  • Proto-Oncogene Proteins c-bcl-2 / biosynthesis
  • Proto-Oncogene Proteins c-bcl-2 / genetics
  • Reactive Oxygen Species / metabolism*
  • Sulfhydryl Compounds / pharmacology*
  • X-Linked Inhibitor of Apoptosis Protein / biosynthesis
  • X-Linked Inhibitor of Apoptosis Protein / genetics

Substances

  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • CASP8 and FADD-Like Apoptosis Regulating Protein
  • CFLAR protein, human
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Neoplasm Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • Reactive Oxygen Species
  • Sulfhydryl Compounds
  • X-Linked Inhibitor of Apoptosis Protein
  • XIAP protein, human
  • methyl 2-cyano-3,11-dioxooleana-1,12-dien-30-oate
  • methyl 2-cyano-3,12-dioxooleana-1, 12-dien-30-oate
  • Glutathione
  • Glycyrrhetinic Acid
  • Acetylcysteine