Abstract
Tumor cells of 14 cases of non-Hodgkin lymphomas and 2 cases of Hodgkin disease were tested for the presence of the transferrin receptor (CD71) by flow cytofluorimetry before 67gallium imaging. It appeared that expression of CD71 phenotype was closely related to the positivity of gallium scan before therapy. We feel that this test is able to predict the avidity for 67gallium and the clinical implications are discussed.
MeSH terms
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Bone Marrow / diagnostic imaging
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Bone Marrow / immunology
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Bone Marrow / ultrastructure
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Flow Cytometry / methods
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Gallium Radioisotopes*
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Hodgkin Disease / diagnostic imaging
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Hodgkin Disease / genetics*
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Hodgkin Disease / immunology
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Humans
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Lymph Nodes / diagnostic imaging
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Lymph Nodes / immunology
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Lymph Nodes / ultrastructure
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Lymphoma, Non-Hodgkin / diagnostic imaging
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Lymphoma, Non-Hodgkin / genetics*
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Lymphoma, Non-Hodgkin / immunology
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Phenotype
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Radionuclide Imaging
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Receptors, Transferrin / genetics*
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Tomography, X-Ray Computed
Substances
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Gallium Radioisotopes
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Receptors, Transferrin