Abstract
A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (phi(em) 12%), allowing the creation of a ratiometric sensory system for pO(2) (versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Apoptosis / drug effects*
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Aza Compounds / chemistry*
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Aza Compounds / pharmacology
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Mice
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Molecular Structure
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NIH 3T3 Cells
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Naphthols / chemistry*
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Oxygen / chemistry*
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Structure-Activity Relationship
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Terbium / chemistry*
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Xanthones / chemistry*
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Xanthones / pharmacology
Substances
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Aza Compounds
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Naphthols
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Xanthones
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Terbium
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xanthone
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Oxygen