Complete resolution of universal calcinosis in a patient with juvenile dermatomyositis using pamidronate

Samy Slimani; Amina Abdessemed; Assia Haddouche; Aicha Ladjouze-Rezig

doi:10.1016/j.jbspin.2009.04.011

Complete resolution of universal calcinosis in a patient with juvenile dermatomyositis using pamidronate

Joint Bone Spine. 2010 Jan;77(1):70-2. doi: 10.1016/j.jbspin.2009.04.011. Epub 2009 Dec 23.

Authors

Samy Slimani¹, Amina Abdessemed, Assia Haddouche, Aicha Ladjouze-Rezig

Affiliation

¹ Department of Rheumatology, Ben Aknoun Hospital, rue des Deux-Bassins, Ben Aknoun, 16300 Algiers, Algeria. slimani@dr.com

PMID: 20031471
DOI: 10.1016/j.jbspin.2009.04.011

Abstract

A 14-year-old girl with juvenile dermatomyositis developed extensive and debilitating calcinosis, unresponsive to colchicine, while muscle involvement subsided. Pamidronate (2mg/kg/year) produced dramatic improvement of pain and function within 2 months and calcinosis had completely resolved by 2 years. No new calcifications have been noted with a 5-year follow-up.

Publication types

Case Reports

MeSH terms

Adolescent
Bone Density Conservation Agents / therapeutic use*
Calcinosis / diagnostic imaging
Calcinosis / drug therapy*
Calcinosis / etiology
Calcium / administration & dosage
Cholecalciferol / administration & dosage
Dermatomyositis / complications
Dermatomyositis / diagnostic imaging
Dermatomyositis / drug therapy*
Diphosphonates / therapeutic use*
Drug Therapy, Combination
Female
Humans
Methylprednisolone / therapeutic use
Pamidronate
Radiography
Recovery of Function
Treatment Outcome

Substances

Bone Density Conservation Agents
Diphosphonates
Cholecalciferol
Pamidronate
Calcium
Methylprednisolone