Severe toxicity related to a pharmacokinetic interaction between docetaxel and ritonavir in HIV-infected patients

Br J Clin Pharmacol. 2010 Jan;69(1):99-101. doi: 10.1111/j.1365-2125.2009.03555.x.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Antineoplastic Agents / pharmacokinetics*
  • Docetaxel
  • Drug Interactions
  • Exanthema / chemically induced
  • Female
  • HIV Infections / drug therapy*
  • HIV Protease Inhibitors / adverse effects*
  • HIV Protease Inhibitors / pharmacokinetics
  • Humans
  • Male
  • Middle Aged
  • Mucositis / chemically induced
  • Neutropenia / chemically induced*
  • Ritonavir / adverse effects*
  • Ritonavir / pharmacokinetics
  • Seizures, Febrile / chemically induced
  • Taxoids / pharmacokinetics*

Substances

  • Antineoplastic Agents
  • HIV Protease Inhibitors
  • Taxoids
  • Docetaxel
  • Ritonavir