Primary angiitis of the central nervous system: apparent diffusion coefficient lesion analysis

Matthew L White; Yan Zhang

doi:10.1016/j.clinimag.2009.03.007

Primary angiitis of the central nervous system: apparent diffusion coefficient lesion analysis

Clin Imaging. 2010 Jan-Feb;34(1):1-6. doi: 10.1016/j.clinimag.2009.03.007.

Authors

Matthew L White¹, Yan Zhang

Affiliation

¹ Department of Radiology, University of Nebraska Medical Center, Omaha, NE, USA. matthewwhite@unmc.edu

PMID: 20122512
DOI: 10.1016/j.clinimag.2009.03.007

Abstract

Apparent diffusion coefficients (ADCs) of the brain lesions in primary angiitis of the central nervous system (PACNS) patients were analyzed in this study. The mean ADC ratios for acute/subacute phase lesions were significantly lower than that for chronic phase lesions. However, some acute/subacute phase lesions had elevated ADCs and these lesions disappeared overtime, implicating a nonischemic mechanism in PACNS.

Publication types

Evaluation Study

MeSH terms

Adult
Algorithms*
Brain / pathology*
Diffusion Magnetic Resonance Imaging / methods*
Female
Humans
Image Enhancement / methods
Image Interpretation, Computer-Assisted / methods*
Information Storage and Retrieval / methods*
Magnetic Resonance Angiography / methods*
Male
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Vasculitis, Central Nervous System / diagnosis*