Long-term survival outcomes of laparoscopically assisted radical hysterectomy in treating early-stage cervical cancer

Am J Obstet Gynecol. 2010 Aug;203(2):165.e1-7. doi: 10.1016/j.ajog.2010.02.027. Epub 2010 May 11.

Abstract

Objective: The objective of the study was to determine the long-term disease-free and overall survival outcomes of laparoscopic treatment of early-stage cervical cancer.

Study design: This was a longitudinal study of prospectively registered patients of cervical cancer undergoing laparoscopic surgery from June 1994 to December 2005.

Results: A total of 139 patients were included, in which 60 patients were in International Federation of Gynecology and Obstetrics stage IA, 76 in IB, and 3 in IIA. Mean operation time was 231.1 +/- 6.1 minutes. Median number of pelvic lymph node retrieval was 16. Major intraoperative complications included 1 great vessel injury, 1 ureteral injury, 1 colon injury, and 6 cystotomies. In a median follow-up of 92.1 months, the mean +/- SEM cumulative disease-free and overall survival rates were 91.01% +/- 2.77% and 92.78% +/- 3.06%, respectively.

Conclusion: The laparoscopic approach has favorable long-term survival outcomes and perioperative morbidity. With the advantage of minimal invasiveness, laparoscopic treatment by experienced surgeons is an ideal alternative for early-stage cervical cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biopsy, Needle
  • China
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Hysterectomy / methods*
  • Hysterectomy / mortality
  • Hysteroscopy / methods
  • Immunohistochemistry
  • Laparoscopy / adverse effects
  • Laparoscopy / methods*
  • Longitudinal Studies
  • Lymph Nodes / pathology
  • Middle Aged
  • Neoplasm Staging
  • Postoperative Complications / mortality
  • Postoperative Complications / physiopathology
  • Prospective Studies
  • Registries
  • Risk Assessment
  • Survival Analysis
  • Time Factors
  • Treatment Outcome
  • Uterine Cervical Neoplasms / mortality*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / surgery*