Sexually transmitted infections (STI) or diseases (STD) are sociologic markers reflecting sexual behaviours of individuals belonging to this society. Since 2000, the evolution of STI has been characterized by the recrudescence of syphilis, the appearance of resistance of gonococcus to fluoroquinolones and the emergence of lymphogranuloma venereum. These STI are nearly exclusively observed in men and predominantly in men having sex with men with a high proportion of HIV infected individuals from 15% in those consulting for gonococcemia to 100% in those diagnosed with lymphogranuloma venereum. The epidemic is relatively stable since 2007 which suggest that it could decline in the next future. Relapse of these STI suggests a relapse of high risks sexual practices in group of patients historically exposed to HIV and that control measures for prevention of STI targeting men having sex with men should be reinforced for controlling the incidence of classical STI and of HIV.