Abstract
The herpes viruses are responsible for a wide range of diseases in patients following transplant, resulting from direct viral effects and indirect effects, including tumor promotion. Effective treatments and prophylaxis exist for the neurotropic herpes viruses HSV-1, HSV-2, varicella zoster virus, and possibly HHV-6. Antivirals seem to be less effective at prevention of the tumor-promoting effects of Epstein-Barr virus and HHV-8. Reduction in immunosuppression is the cornerstone to treatment of many diseases associated with herpes virus infections.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Herpesviridae Infections / epidemiology*
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Herpesviridae Infections / mortality
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Herpesviridae Infections / prevention & control
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Herpesviridae Infections / virology*
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Herpesvirus 1, Human / isolation & purification
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Herpesvirus 2, Human / isolation & purification
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Herpesvirus 3, Human / isolation & purification
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Herpesvirus 4, Human / isolation & purification
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Herpesvirus 6, Human / isolation & purification
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Herpesvirus 7, Human / isolation & purification
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Herpesvirus 8, Human / isolation & purification
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Humans
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Immunosuppressive Agents / adverse effects*
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Transplantation*