Necrotising colitis with perforation in diarrhoic patients treated with loperamide

M Olm; F J Gonzalez; J C Garcia-Valdecasas; J Fuster; A Bertran; J Milla

doi:10.1007/BF00265854

Necrotising colitis with perforation in diarrhoic patients treated with loperamide

Eur J Clin Pharmacol. 1991;40(4):415-6. doi: 10.1007/BF00265854.

Authors

M Olm¹, F J Gonzalez, J C Garcia-Valdecasas, J Fuster, A Bertran, J Milla

Affiliation

¹ Internal Medicine Unit, Hospital Clinico y Provincial, Barcelona, Spain.

PMID: 2050178
DOI: 10.1007/BF00265854

Abstract

Two cases of necrotising enterocolitis with perforation occurred in patients with paralytic ileus after loperamide therapy. The possible role of loperamide in the pathogenesis of the complications is suggested.

Publication types

Case Reports

MeSH terms

Adult
Enterocolitis, Pseudomembranous / chemically induced*
Enterocolitis, Pseudomembranous / physiopathology
Enterocolitis, Pseudomembranous / surgery
Female
Humans
Intestinal Perforation / physiopathology
Intestinal Perforation / surgery*
Loperamide / adverse effects*

Substances

Loperamide