Nasal application of rBet v 1 or non-IgE-reactive T-cell epitope-containing rBet v 1 fragments has different effects on systemic allergen-specific antibody responses

J Allergy Clin Immunol. 2010 Dec;126(6):1312-5.e4. doi: 10.1016/j.jaci.2010.06.008. Epub 2010 Jul 31.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Adult
  • Allergens / immunology
  • Antibody Formation
  • Antigens, Plant / immunology
  • Antigens, Plant / metabolism*
  • Betula / immunology
  • Desensitization, Immunologic*
  • Epitopes
  • Epitopes, T-Lymphocyte / immunology
  • Epitopes, T-Lymphocyte / metabolism*
  • Female
  • Humans
  • Immunoglobulin E / blood
  • Male
  • Nasal Obstruction
  • Peptide Fragments / immunology
  • Peptide Fragments / metabolism*
  • Pollen / adverse effects
  • Protein Binding
  • Rhinitis, Allergic, Seasonal / drug therapy
  • Rhinitis, Allergic, Seasonal / immunology*
  • Rhinitis, Allergic, Seasonal / pathology
  • Rhinitis, Allergic, Seasonal / physiopathology

Substances

  • Allergens
  • Antigens, Plant
  • Epitopes
  • Epitopes, T-Lymphocyte
  • Peptide Fragments
  • Immunoglobulin E