Role of bacteria in oncogenesis

Clin Microbiol Rev. 2010 Oct;23(4):837-57. doi: 10.1128/CMR.00012-10.

Abstract

Although scientific knowledge in viral oncology has exploded in the 20th century, the role of bacteria as mediators of oncogenesis has been less well elucidated. Understanding bacterial carcinogenesis has become increasingly important as a possible means of cancer prevention. This review summarizes clinical, epidemiological, and experimental evidence as well as possible mechanisms of bacterial induction of or protection from malignancy.

Publication types

  • Review

MeSH terms

  • Bacterial Infections / complications*
  • Cell Transformation, Neoplastic
  • Humans
  • Neoplasms / etiology*
  • Neoplasms / microbiology*
  • Oncolytic Viruses / pathogenicity*
  • Oncolytic Viruses / physiology