Linking cell signaling and the epigenetic machinery

Helai P Mohammad; Stephen B Baylin

doi:10.1038/nbt1010-1033

Linking cell signaling and the epigenetic machinery

Nat Biotechnol. 2010 Oct;28(10):1033-8. doi: 10.1038/nbt1010-1033.

Authors

Helai P Mohammad¹, Stephen B Baylin

Affiliation

¹ Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

PMID: 20944593
DOI: 10.1038/nbt1010-1033

Abstract

One of the biggest gaps in our knowledge about epigenomes is how their interplay with cellular signaling influences development, adult cellular differentiation and disease.

MeSH terms

Cell Proliferation
Cells / metabolism*
Chromatin Assembly and Disassembly / genetics
Disease / genetics
Embryo, Mammalian / metabolism
Epigenesis, Genetic*
Epigenomics
Humans
Models, Genetic
Pluripotent Stem Cells / cytology
Pluripotent Stem Cells / metabolism
Signal Transduction*