The present study compares the efficacy of various disinfectants against Bacillus anthracis spores. While Bleach Rite(®) and 10% bleach reduce spore numbers by 90% within 10 minutes, a long contact time is required for complete disinfection. By contrast, although SporGon(®) did not initially reduce the number of spores as quickly as Bleach Rite or 10% bleach, shorter contact times were required for complete eradication of viable spores.