Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice

Luqian Zhao; Chuanfeng Zhou; Jian Zhang; Fu Gao; Bailong Li; Yunhai Chuai; Cong Liu; Jianming Cai

doi:10.7150/ijbs.7.297

Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice

Int J Biol Sci. 2011 Mar 25;7(3):297-300. doi: 10.7150/ijbs.7.297.

Authors

Luqian Zhao¹, Chuanfeng Zhou, Jian Zhang, Fu Gao, Bailong Li, Yunhai Chuai, Cong Liu, Jianming Cai

Affiliation

¹ Department of Radiation Medicine, Second Military Medical University, Xiangyin Road, Shanghai 200433, PR China.

Abstract

Ionizing radiation (IR) is a well-known carcinogen, however the mechanism of radiation induced thymic lymphoma is not well known. Moreover, an easy and effective method to protect mice from radiation induced thymic lymphoma is still unknown. Hydrogen, or H(2), is seldom regarded as an important agent in medical usage, especially as a therapeutic gas. Here in this study, we found that H(2) protects mice from radiation induced thymic lymphoma in BALB/c mice.

Keywords: Ionizing radiation; thymic lymphoma.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Hydrogen / therapeutic use*
Lymphoma / prevention & control*
Mice
Mice, Inbred BALB C
Neoplasms, Radiation-Induced / prevention & control*
Radiation, Ionizing
Radiation-Protective Agents / therapeutic use*
Reactive Oxygen Species / metabolism
Thymus Neoplasms / prevention & control*

Substances

Radiation-Protective Agents
Reactive Oxygen Species
Hydrogen