Argonaute10 as a miRNA locker

Pablo A Manavella; Detlef Weigel; Liang Wu

doi:10.1016/j.cell.2011.03.045

Argonaute10 as a miRNA locker

Cell. 2011 Apr 15;145(2):173-4. doi: 10.1016/j.cell.2011.03.045.

Authors

Pablo A Manavella¹, Detlef Weigel, Liang Wu

Affiliation

¹ Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

PMID: 21496638
DOI: 10.1016/j.cell.2011.03.045

Abstract

The stability and translation efficiency of many messenger RNAs is regulated by microRNAs (miRNAs), which exert their effects through associated Argonaute proteins. In this issue, Zhu, Zhang, and colleagues reveal that plants also exploit miRNA binding by Argonautes as a sequestering mechanism that prevents miRNAs from fulfilling their normal roles.

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