False aneurysm infected by Aspergillus fumigatus: an unusual complication of aortofemoral bypass graft

Ann Vasc Surg. 1990 Jul;4(4):388-92. doi: 10.1007/BF02000506.

Abstract

Two cases of Aspergillus fumigatus infection of aortobifemoral prosthetic grafts are reported. Both patients were treated successfully by excision of the infected prosthetic material, axillofemoral extra-anatomic bypass, and prolonged medical treatment. The patients received amphotericin B, 5-flucytosine and itraconazole until negative aspergillus serology was obtained (at 9 and 18 months, respectively). Later, repeat disobliteration procedures for thrombosis of the axillofemoral bypass were required. No recurrent aspergillus infection was found.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Aneurysm, Infected / drug therapy
  • Aneurysm, Infected / etiology
  • Aneurysm, Infected / surgery*
  • Antifungal Agents / therapeutic use
  • Aorta, Abdominal / surgery*
  • Aspergillosis / drug therapy
  • Aspergillosis / etiology
  • Aspergillosis / surgery*
  • Aspergillus fumigatus
  • Blood Vessel Prosthesis / adverse effects*
  • Femoral Artery / surgery*
  • Flucytosine / therapeutic use
  • Humans
  • Itraconazole
  • Ketoconazole / analogs & derivatives
  • Ketoconazole / therapeutic use
  • Male
  • Middle Aged

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B
  • Flucytosine
  • Ketoconazole