Abstract
Two cases of Aspergillus fumigatus infection of aortobifemoral prosthetic grafts are reported. Both patients were treated successfully by excision of the infected prosthetic material, axillofemoral extra-anatomic bypass, and prolonged medical treatment. The patients received amphotericin B, 5-flucytosine and itraconazole until negative aspergillus serology was obtained (at 9 and 18 months, respectively). Later, repeat disobliteration procedures for thrombosis of the axillofemoral bypass were required. No recurrent aspergillus infection was found.
MeSH terms
-
Amphotericin B / therapeutic use
-
Aneurysm, Infected / drug therapy
-
Aneurysm, Infected / etiology
-
Aneurysm, Infected / surgery*
-
Antifungal Agents / therapeutic use
-
Aorta, Abdominal / surgery*
-
Aspergillosis / drug therapy
-
Aspergillosis / etiology
-
Aspergillosis / surgery*
-
Aspergillus fumigatus
-
Blood Vessel Prosthesis / adverse effects*
-
Femoral Artery / surgery*
-
Flucytosine / therapeutic use
-
Humans
-
Itraconazole
-
Ketoconazole / analogs & derivatives
-
Ketoconazole / therapeutic use
-
Male
-
Middle Aged
Substances
-
Antifungal Agents
-
Itraconazole
-
Amphotericin B
-
Flucytosine
-
Ketoconazole