Abstract
Incubation of quercetin with Cunninghamella elegans ATCC 9245 yielded three metabolites, including quercetin 3-O-β-D-glucopyranoside, kaempferol 3-O-β-D-glucopyranoside and isorhamnetin 3-O-β-D-glucopyranoside. Glucosylation, O-methylation and dehydroxylation were involved in the process, among which dehydroxylation has never been found in Cunninghamella. Quercetin was completely metabolized in 72 h.
Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cunninghamella / metabolism*
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Flavonols / chemistry
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Flavonols / metabolism
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Glucosides / chemistry
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Glucosides / metabolism
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Humans
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Kaempferols / chemistry
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Kaempferols / metabolism
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Monosaccharides / chemistry
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Monosaccharides / metabolism
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Quercetin / analogs & derivatives
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Quercetin / chemistry
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Quercetin / metabolism*
Substances
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Flavonols
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Glucosides
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Kaempferols
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Monosaccharides
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quercetin-3'-O-beta-D-glucopyranoside
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Quercetin
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astragalin
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isorhamnetin 3-O-glucoside
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quercetin 3-O-glucopyranoside